Computational Methods for Characterizing Cancer Mutational Heterogeneity
نویسندگان
چکیده
منابع مشابه
Computational Methods for Characterizing Cancer Mutational Heterogeneity
Advances in DNA sequencing technologies have allowed the characterization of somatic mutations in a large number of cancer genomes at an unprecedented level of detail, revealing the extreme genetic heterogeneity of cancer at two different levels: inter-tumor, with different patients of the same cancer type presenting different collections of somatic mutations, and intra-tumor, with different cl...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2017
ISSN: 1664-8021
DOI: 10.3389/fgene.2017.00083